Headaches >> Imitrex

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Imitrex is taken for:

The treatment of migraine headaches with or without aura (eg, flashing lights, wavy lines, dark spots). It is and taken to treat cluster headaches.

Imitrex is a serotonin 5-HT ₁receptor agonist ("triptan"). It works by narrowing blood vessels in the brain, which helps to relieve migraine and cluster headaches.

Do NOT use Imitrex if:

• you are allergic to any ingredient in Imitrex
• you have a history of ischemic heart disease (eg, angina, heart attack), coronary artery disease (CAD), other moderate to severe heart problems, brain blood vessel disease (eg, stroke, transient ischemic attack), or other blood vessel disease (eg, Raynaud syndrome, ischemic bowel disease)
• you have uncontrolled tall blood pressure or severe liver problems
• you have certain types of migraines (eg, hemiplegic, basilar)
• you have taken certain other migraine medicines within the past 24 hours. These include an ergot derivative (eg, dihydroergotamine, methysergide) or another serotonin 5-HT ₁ receptor agonist (eg, eletriptan, rizatriptan)
• you are taking sibutramine

Contact your physician or health care provider right away if any of these apply to you.

Before taking Imitrex :

Some medical conditions might interact with Imitrex . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have history of liver or kidney problems, seizures (eg epilepsy), or heart problems
• if you have shortness of breath, chest pain, or a history of tall blood pressure, heart attack, stroke, tall cholesterol, diabetes, or smoking
• if you are a woman who is past menopause
• if you are a man who is older than 40 years of age
• if you are very overweight
• if a family member has had heart disease

Some MEDICINES MIGHT INTERACT with Imitrex . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin norepinephrine reuptake inhibitors (eg, duloxetine), orsibutramine because the risk of a serious side effect called serotonin syndrome might be increased. Symptoms of serotonin syndrome might include mental or mood changes, hallucinations, fast heartbeat, fever, loss of coordination, muscle spasms, increased sweating, nausea, vomiting, or diarrhea
• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because they might increase the risk of Imitrex 's side effects
• Ergot derivatives (eg, dihydroergotamine, methysergide) or other serotonin 5-HT ₁ receptor agonists (eg, eletriptan, rizatriptan) because the risk of their side effects might be increased by Imitrex

This might not be a complete list of all interactions that might occur. Ask your health care provider if Imitrex might interact with other medicines that you use. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Imitrex :

Use Imitrex as directed by your physician. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Imitrex . Talk to your pharmacist if you have questions about this information.
• A health care provider will teach you how to use Imitrex . Be sure you understand how to use Imitrex . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Do not use Imitrex if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
• Inject Imitrex just under the skin. Do NOT inject Imitrex into a muscle or a blood vessel. Talk with your health care provider about suitable injection sites, how to load an autoinjector device, and how to give an injection.
• Imitrex will relieve migraine pain at any time during an attack. It is better to inject a dose of Imitrex as soon as you notice symptoms of a migraine attack.
• If your migraine symptoms go away and then come back, you might use a second dose as directed by your physician. Wait at least 1 hour between doses.
• If your symptoms do not improve after the first injection, do not use a second dose for the equal attack. Contact your physician.
• Do not use more than 2 doses in a 24-hour period or treat more than 4 headaches within 30 days without checking with your physician.
• Do not throw away the autoinjector.
• Store this product, and syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
• If you miss a dose of Imitrex and you still have a headache, follow your doctor's dosing instructions. Contact your physician if you are unsure of what to do if you miss a dose. Do not use Imitrex more often than prescribed. Do not use 2 doses at one time.

Ask your health care provider any questions you might have about how to use Imitrex .

Important safety information:

• Imitrex might cause drowsiness or dizziness. These effects might be worse if you use it with alcohol or certain medicines. Use Imitrex with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Rarely, serious heart problems (eg, heart attack, rough heartbeat) have been reported within a few hours of taking Imitrex . Contact your physician at one time if fast or rough heartbeat; chest, jaw, or neck pain or numbness; numbness of an arm or leg; severe stomach pain, dizziness, or vomiting; fainting; or vision changes occur. Discuss any questions or concerns with your physician.
• Imitrex should not be taken to stop or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your physician before taking Imitrex .
• Do NOT use more than the recommended dose without checking with your physician.
• Lab tests, including heart function tests, might be performed while you use Imitrex . These tests might be taken to monitor your condition or check for side effects. Be sure to store all physician and lab appointments.
• Imitrex should not be taken in the ELDERLY; the risk of serious side heart and blood pressure side effects might be increased.
• Imitrex should not be taken in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is not known if Imitrex can cause harm to the fetus. If you become pregnant, contact your physician. You will need to discuss the benefits and risks of taking Imitrex while you are pregnant. Imitrex is found in breast milk. If you are or will be breast-feeding while you use Imitrex , check with your physician. Discuss any possible risks to your baby.

Possible side effects of Imitrex :

All medicines might cause side effects, however many people have no, or minor, side effects. Check with your physician if any of these most GENERAL side effects persist or become bothersome:

Burning, numbness, or tingling of the skin; dizziness; drowsiness; feeling of heaviness, pressure, or tightness; feeling strange; mild, temporary flushing; muscle aches; nausea; neck stiffness; pain, swelling, or redness at the injection site; ill feeling; throat or sinus discomfort; shut feeling in the head; tingling; tiredness; vomiting; warm/hot sensation; weakness.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; chest pain; confusion; fainting; fast or rough heartbeat; hearing problems; numbness or tingling of an arm or leg; one-sided weakness; pain, tightness, or pressure in the jaw, neck, or chest; seizures; severe headache, dizziness, or vomiting; severe or prolonged flushing; severe stomach pain; shortness of breath; speech changes; very cold or blue fingers or toes; vision changes or loss of vision; wheezing.

This is not a complete list of all side effects that might occur. If you have questions or need medical advice about side effects, contact your physician or health care provider. You might report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms might include blue skin or lips; chest pain; dilated pupils; loss of coordination; paralysis; redness of the fingers or toes; seizures; slow or difficult breathing; tremor.

Store Imitrex between 36 and 86 degrees F (2 and 30 degrees C). Store away from heat, moisture, and thin. Do not freeze. Do not store at temperatures above 86 degrees F (30 degrees C). Do not store in the bathroom. Store Imitrex in the case provided. Throw away expired medicine as directed by your physician (the expiration date is printed on the treatment pack). Do not throw away the autoinjector. Store Imitrex out of the reach of children and away from pets.

General information:

• If you have any questions about Imitrex , please talk with your physician, pharmacist, or other health care provider.
• Imitrex is to be taken only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your physician.

This information is a summary only. It does not contain all information about Imitrex . If you have questions about the medicine you are taking or would like more information, check with your physician, pharmacist, or other health care provider.

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